試題詳解

19. Seahorse XFe analyzer is designed to measure oxygen consumption rate. Which of the following drug can be added to measure the maximum oxygen consumption rate of cells to estimate the maximal mitochondrial function?
(A) High concentration of glucose.
(B) Substrate of Isocitrate dehydrogenase, Isocitrate.
(C) CarbonyI cyanide-p-trifluoromethoxyphenyIhydrazone (FCCP): uncouplers which disrupt the permeability of the inner membrane.
(D) High concentration of pyruvate.
(E) Antimycin A: complex Ill inhibitor.