45. 對於 non-Th2 氣喘的發炎反應，下列何者為非? (A) Both Th1 and Th 17-driven inflammation can lead to airway obstruction and exacerbate an asthma phenotype (B) IL-1 could contribute to asthma phenotype by causing airway hyperresponsiveness, by recruiting neutrophils. (C) Th 17 activity has positive correlation with asthma severity (D) Th 17-mediated inflammation may coexist with Th2-high phenotype and augment Th2 response.