試題詳解

54. Proteins can be modified with small regulatory proteins like ubiquitins and small ubiquitin-like protein modifiers (SUMO). Which of the following descriptions about SUMO is NOT correct?
(A) SUMO are a highly conserved family of proteins found in all eucaryotes.
(B) SUMO are covalently ligated to lysine residues in target proteins.
(C) Sumoylated proteins are primarily targeted to the proteasome for destruction.
(D) Protein sumoylation is primarily a 3-enzyme conjugating system.
(E) Protein sumoylation can be reversed by a small number of isopeptidases that cleave the target protein-SUMO linkages.